the combined effects of aloe vera gel and silver nanoparticles on wound healing in rats

Authors

y. yousefpoor department of nanotechnology, college of advanced sciences and technology in medicine, tehran university of medical sciences, tehran, iran

nanomedine group, college of applied advanced technology in medicine, iran university of medical sciences, tehran, iran

khalilabad health center, mashhad university of medical sciences, mashhad, iranسازمان اصلی تایید شده: دانشگاه علوم پزشکی مشهد (mashhad university of medical sciences)

b. bolouri department of nanotechnology, college of advanced sciences and technology in medicine, tehran university of medical sciences, tehran, iran

abstract

objective(s): this study was aimed at investigating the synergy effects of aloe vera gel and silver nanoparticles on the healing rate of the cutting wounds. materials and methods: in order to determine the concentration of silver nanoparticles in aloe vera gel, the mbc methods were applied on the most common bacteria infecting wounds, staphylococcus aureus, escherichia coli, pseudomonas aeruginosa. the cutting wounds with full-thickness skin were dorsally created on rats; then the rats were divided into 4 groups. the treatments groups included: mixture of aloe vera gel and silver nanoparticles, aloe vera gel alone and silver nanoparticles alone in addition to control groups. the treatment was carried out for 2 weeks and the size of the wound closures were measured by an image software analysis. results:there was no significant difference (p< 0.05) in healing rate between the control and mixture group. however, there were significant differences between the silver nanoparticles and aloe vera groups using tukey's analysis on the 6th, 8th and 10th days. conclusion:the aloe vera gel increased the rate of wound healing whereas the silver nanoparticles had a delay effect; and when they were mixed, it was similar to the average effect of both aloe vera gel and silver nanoparticles.

Upgrade to premium to download articles

Sign up to access the full text

Already have an account?login

similar resources

The combined effects of Aloe vera gel and silver nanoparticles on wound healing in rats

Objective(s): This study was aimed at investigating the synergy effects of Aloe vera gel and silver nanoparticles on the healing rate of the cutting wounds. Materials and Methods: In order to determine the concentration of silver nanoparticles in Aloe vera gel, the MBC methods were applied on the most common bacteria infecting wounds, Staphylococcus aureus, Escherichia coli, Pseudomonas aerugin...

full text

Effects of Minoxidil Gel on Burn Wound Healing in Rats

Background: Minoxidil has been reported to inhibit in vitro fibroblast proliferation and lysyl hydroxylase activity, a key enzyme in collagen biosynthesis. These in-vitro effects proposed minoxidil to be a potential antifibrotic agent. The present study aimed to investigate the effects of minoxidil gel on wound healing procedure in a second-degree burn model in rats.  Materials and methods: Wis...

full text

Effects of Minoxidil Gel on Burn Wound Healing in Rats

Background: Minoxidil has been reported to inhibit in vitro fibroblast proliferation and lysyl hydroxylase activity, a key enzyme in collagen biosynthesis. These in-vitro effects proposed minoxidil to be a potential antifibrotic agent. The present study aimed to investigate the effects of minoxidil gel on wound healing procedure in a second-degree burn model in rats.  Materials and methods: Wis...

full text

Aloe vera gel and thyroid hormone cream may improve wound healing in Wistar rats

Therapeutic effects of various treatment options in wound healing have been one of the most controversial issues in surgical science. The present study was carried out to examine and compare the effects of Aloe vera gel, thyroid hormone cream and silver sulfadiazine cream onsutured incisions in Wistar rats. In a randomized controlled trial, thirty-six Wistar male rats, 250 to 300 g, received su...

full text

study the effects of low level laser diode on no production and healing of diabetic and cortisone acetate and normal wounded sd rats

nitric oxide (no) is a small molecule synthesized by most of mammalian cells with diverse biological activities including vasodilatation, host defense and wound healing. impaired wound healing is a common occurrence among diabetics and patients receiving glucocorticoid therapy. on the other hand the application of laser in biomedical area have been increased. thus, the current studies were desi...

15 صفحه اول

Healing Effect of Aloe Vera on Wound in Albino Mice

Present study is an attempt to investigate wound healing efficiency of Aloe verajuice on excision wound model.This study was undertaken to evaluate the wound healing properties of Aloe vera, for purpose different conc. of Aloe vera juicewere applied with respect toBetadine on excision wound in albino mice.The effect of Aloe vera juice application on excision wound contraction (area in mm 2 ) in...

full text

My Resources

Save resource for easier access later


Journal title:
nanomedicine journal

جلد ۳، شماره ۱، صفحات ۵۷-۶۴

Hosted on Doprax cloud platform doprax.com

copyright © 2015-2023